PROGESTINS UPREGULATE FKBP51 EXPRESSION IN HUMAN ENDOMETRIAL STROMAL CELLS TO INDUCE FUNCTIONAL PROGESTERONE AND GLUCOCORTICOID WITHDRAWAL: IMPLICATIONS FOR CONTRACEPTIVE- ASSOCIATED ABNORMAL UTERINE BLEEDING.

Use of long-acting progestin only contraceptives (LAPCs) offers a discrete and highly effective family planning method.Abnormal uterine bleeding (AUB) is the major side effect of, and cause for, discontinuation of LAPCs.The endometria of LAPC-treated women display abnormally enlarged, fragile blood vessels, decreased endometrial blood flow and oxid

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Abstract Background Fertilization restores the diploid state and begins the process by which the single-cell oocyte is converted into a polarized, multicellular organism.In the nematode, Caenorhabditis elegans, two of the earliest events following fertilization are secretion of the chitinous eggshell and completion of meiosis, and in this report we

mohair torquay Apical neural progenitors (aNPs) drive neurogenesis by means of a program consisting of self-proliferative and neurogenic divisions.The balance between these two manners of division sustains the pool of apical progenitors into late neurogenesis, thereby ensuring their availability to populate the brain with terminal cell types.Using

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